CDM Tables

Patient

Data used to configure the patient.

Property Name Type Definition
Age SEScalarTime Patient age.
BasalMetabolicRate SEScalarPower The life-sustaining metabolic rate.
BodyFatFraction SEScalar0To1 Total mass of fat divided by total body mass; body fat includes essential body fat and storage body fat.
DiastolicArterialPressureBaseline SEScalarPressure The starting minimum pressure in the aorta over the course of a cardiac cycle.
BodyDensity SEScalarMassPerVolume The mass of the body divided by the volume of the body.
ExpiratoryReserveVolume SEScalarVolume The maximum amount of air that can be exhaled from the end-expiratory position.
HeartRateBaseline SEScalarFrequency The resting heart rate.
RightLungRatio SEScalar0To1 The ratio of total lung surface area that is associated with the right lung.
Name String Patient Identifier.
Height SEScalarLength Patient height.
RespirationRateBaseline SEScalarFrequency The resting respiration rate.
ResidualVolume SEScalarVolume The volume of air remaining in the lungs after a maximal exhalation.
FunctionalResidualCapacity SEScalarVolume The volume of air remaining in the lungs after a passive expiration.
InspiratoryReserveVolume SEScalarVolume The maximal volume that can be inhaled from the end-inspiratory level.
TidalVolumeBaseline SEScalarVolume The starting volume of air moved into or out of the lungs during normal respiration.
VitalCapacity SEScalarVolume The maximum amount of air a person can expel from their lungs after a maximum inhalation.
Sex eSex Enumeration for patient sex.
SkinSurfaceArea SEScalarArea The surface area of the skin surface of the body.
HeartRateMaximum SEScalarFrequency The maximum heart rate the patient can withstand.
AlveoliSurfaceArea SEScalarArea The surface area of the alveoli for gas diffusion.
MeanArterialPressureBaseline SEScalarPressure The resting mean arterial pressure.
Weight SEScalarMass Patient weight.
InspiratoryCapacity SEScalarVolume The sum of IRV and TV.
BloodVolumeBaseline SEScalarVolume The total volume of fluid within the cardiovascular system.
SystolicArterialPressureBaseline SEScalarPressure The starting maximum pressure in the aorta over the course of a cardiac cycle.
LeanBodyMass SEScalarMass Component of body composition after subtracting body fat weight.
HeartRateMinimum SEScalarFrequency The minimum heart rate the patient can withstand.
TotalLungCapacity SEScalarVolume The volume of air in the lungs at maximal inflation.

PatientData_eEvent

Enumeration for states the patient can enter and exit out of.

Property Name Type Definition
Antidiuresis eEvent Low urine flow.
Asystole eEvent Represents no cardiac electrical activity.
Bradycardia eEvent The heart rate is slowed to below 60 beats per minute.
Bradypnea eEvent The state at which the respiratory rate has fallen 10 breaths per minute.
BrainOxygenDeficit eEvent A lack of oxygen in the brain. Death will occur ~30min.
CardiacArrest eEvent Sudden, unexpected loss of heart function, breathing, and consciousness.
CardiogenicShock eEvent Inadequate blood circulation due to failure of the heart ventricles (Cardiac Index < 2.2 L/min m2).
CriticalBrainOxygenDeficit eEvent A critical lack of oxygen in the brain. Death in under 10min.
Dehydration eEvent A loss of more fluid than is taken in (More than 3% loss of resting fluid mass).
Diuresis eEvent High urine flow.
Fasciculation eEvent Brief spontaneous contractions of muscle fibers.
Fatigue eEvent The body is using energy above the Basal Metabolic Rate.
FunctionalIncontinence eEvent Uncontrolled bladder release due to a full bladder.
Hypercapnia eEvent State at which the arterial carbon dioxide partial pressure has exceeded 60 mmHg.
Hyperglycemia eEvent An excess of glucose in the bloodstream (> 200 mg/dL).
Hyperthermia eEvent The condition of having a body temperature greatly above normal (> 38 C).
Hypoglycemia eEvent Low glucose in the bloodstream (< 70 mg/dL).
Hypothermia eEvent The condition of having a body temperature greatly below normal (< 35 C).
Hypoxia eEvent State at which the arterial oxygen partial pressure has fallen below 65 mmHg.
HypovolemicShock eEvent The blood volume has dropped below 65% of its normal value.
IntracranialHypertension eEvent Intracranial pressure is greater than 25 mmHg.
IntracranialHypotension eEvent Intracranial pressure is lower than 7 mmHg.
IrreversibleState eEvent An unrecoverable patient state. The engine will cease calculating when this event occurs.
Ketoacidosis eEvent A form of metabolic acidosis where the anion gap is driven by the rise in ketones.
LacticAcidosis eEvent A form of metabolic acidosis where the blood lactate concentration rises.
MaximumPulmonaryVentilationRate eEvent The maximum pulmonary ventilation rate has been reached.
MetabolicAcidosis eEvent A condition where the body is producing excess acids. (pH < 7.35).
MetabolicAlkalosis eEvent A condition where the body is producing excess bases. (pH > 7.45).
MildAcuteRespiratoryDistress eEvent Mild imparement of the alveoli, reducing gas exchange within the lungs. (CarricoIndex [201,300] mmHg)
ModerateAcuteRespiratoryDistress eEvent Moderate imparement of the alveoli, reducing gas exchange within the lungs. (CarricoIndex [101,200] mmHg)
MyocardiumOxygenDeficit eEvent The myocardium oxygen level has decreased below 5 mmHg.
Natriuresis eEvent Sodium excreation above normal levels.
NutritionDepleted eEvent The stomach is empty.
PulselessRhythm eEvent The state at which the heart has stopped beating.
RenalHypoperfusion eEvent Low blood flow to the kidneys.
RespiratoryAcidosis eEvent An increase of CO2 concentration in the bloodstream and a decrease in blood pH.
RespiratoryAlkalosis eEvent An decrease of CO2 concentration in the bloodstream and a increase in blood pH.
StartOfCardiacCycle eEvent The Patient is starting a new heart beat.
StartOfExhale eEvent Patient is starting to exhale.
StartOfInhale eEvent Patient is starting to inhale.
SevereAcuteRespiratoryDistress eEvent Severe imparement of the alveoli, reducing gas exchange within the lungs. (CarricoIndex [0,100] mmHg)
Tachycardia eEvent The heart rate is elevated above 100 beats per minute.
Tachypnea eEvent A breathing rate above 20 breaths per minute.
UNRECOGNIZED eEvent

Tension Pneumothorax

A pneumothorax is an abnormal collection of air or gas in the pleural space that separates the lung from the chest wall. Like pleural effusion (liquid buildup in that space), pneumothorax may interfere with normal breathing.

Property Name Type Definition
Severity SEScalar0To1
Side eSide
Type eGate

Conscious Respiration

An ordered list of concious breath commands for the patient to preform.

Property Name Type Definition
Commands List of CommandsBreathHoldTable
ForcedExhaleTable
ForcedInhaleTable
UseInhalerTable

Substance Infusion

Continuous injection of a specific substance.

Property Name Type Definition
Rate SEScalarVolumePerTime
Substance SESubstance SubstanceTable
Concentration SEScalarMassPerVolume

Needle Decompression

A 14-16G intravenous caninula is inserted into the second rib-space in the mid-clavcular line. The needle is advanced until air can be aspirated into a connecting syringe. The needle is withdrawn and the caninula is left to allow air flow out of the pleural space. This effectively converts the closed pneumothorax into an open pneumothorax.

Property Name Type Definition
Side eSide

Asthma Attack

Property Name Type Definition
Severity SEScalar0To1

Bronchoconstriction

Constriction of the airways in the lungs due to tightening of surrounding smooth muscle.

Property Name Type Definition
Severity SEScalar0To1

Mechanical Ventilation

Mechanically breathing for the patient, such as with a squeeze bag or other equipment.

Property Name Type Definition
Flow SEScalarVolumePerTime Flow produced.
GasFraction List of SESubstanceFractionAmountSubstanceFractionAmountTable
Pressure SEScalarPressure Pressure produced.

Substance Compound Infusion

Continuous injection of a compound.

Property Name Type Definition
BagVolume SEScalarVolume
Rate SEScalarVolumePerTime
SubstanceCompound SESubstanceCompound SubstanceCompoundTable

Airway Obstruction

A blockage of the Airway leading to no respiration/air flow in or out of the body.

Property Name Type Definition
Severity SEScalar0To1

Acute Stress

Fight or flight. The body prepares to defend itself.

Property Name Type Definition
Severity SEScalar0To1

Chest Compression Force Scale

Technique used when performing cardiopulmonary resuscitation. Application of external force to the chest cavity in order to pump blood through the heart.

Property Name Type Definition
ForceScale SEScalar0To1 A fractional representation of the maximum force that can be applied to the chest: 0.0 is no force applied, 1.0 is maximum force applied.
ForcePeriod SEScalarTime The specified length of time the force is applied.

Chest Compression Force

Technique used when performing cardiopulmonary resuscitation. Application of external force to the chest cavity in order to pump blood through the heart.

Property Name Type Definition
Force SEScalarForce

Urinate

Empty the bladder of its contents.

Chest Occlusive Dressing

Applies an occlusive dressing to either the left or right side of the chest. An occlusive dressing is an air and water-tight trauma dressing that provides immediate control of pressure and bleeding that occurs with an open pneumothorax.

Property Name Type Definition
Side eSide

Patient Assessment Request

Property Name Type Definition
Type eType

Cardiac Arrest

Applies a non-specific cardiac arrest.

Apnea

Reduction of achieved tidal volume by inhibiting the respiratory breathing mechanism (i.e., muscles of respiration). Maximum severity will stop breathing completely.

Property Name Type Definition
Severity SEScalar0To1

Brain Injury

A non-localized traumatic brain injury.

Property Name Type Definition
Severity SEScalar0To1
Type eType

Exercise

Increase the patient's metabolic rate leading to an increase in core temperature, cardiac output, respiration rate and tidal volume.

Property Name Type Definition
Intensity SEScalar0To1 Fractional representation of the maximum patient exertion.

Substance Bolus

An administration of a substance that is given all at one time to raise its concentration in blood to an effective level.

Property Name Type Definition
Substance SESubstance SubstanceTable
Dose SEScalarVolume
AdminRoute eAdministrationRoute
Concentration SEScalarMassPerVolume

Pericardial Effusion

Pericardial effusion ("fluid around the heart") is an abnormal accumulation of fluid in the pericardial cavity. Because of the limited amount of space in the pericardial cavity, fluid accumulation leads to an increased intrapericardial pressure which can negatively affect heart function. A pericardial effusion with enough pressure to adversely affect heart function is called cardiac tamponade. Pericardial effusion usually results from a disturbed equilibrium between the production andre-absorption of pericardial fluid, or from a structural abnormality that allows fluid to enter the pericardial cavity. Normal levels of pericardial fluid are from 15 to 50 mL.

Property Name Type Definition
EffusionRate SEScalarVolumePerTime

Hemorrhage

A hemorrhage is the loss of blood escaping from the circulatory system. Typically, a healthy person can endure a loss of 10 to 15 percent of the total blood volume without serious medical difficulties.

Property Name Type Definition
Rate SEScalarVolumePerTime The flow rate of blood exiting the specified compartment. Set to zero to stop the bleeding rate.
Compartment String Compartment where the bleeding is occuring.

Intubation

Insertion of tube into the patient's airway.

Property Name Type Definition
Type eType

Consume Nutrients

Consume nutrients into the body.

Property Name Type Definition
NutritionFile String
Nutrition SENutrition NutritionTable

Forced Exhale

Property Name Type Definition
ExpiratoryReserveVolumeFraction SEScalar0To1
Period SEScalarTime

Use Inhaler

Breath Hold

Property Name Type Definition
Period SEScalarTime

Forced Inhale

Property Name Type Definition
InspiratoryCapacityFraction SEScalar0To1
Period SEScalarTime

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD) is an obstructive lung disease characterized by chronically reduced airflow into the lungs. Unlike asthma, the reduction in airflow does not generally improve with medication. When tissue damage occurs primarily in the airways, the condition is called chronic bronchitis. When tissue destruction is focused in the alveoli, the condition is called emphysema. COPD is a manifestation of both conditions, although one condition may dominate.

Property Name Type Definition
EmphysemaSeverity SEScalar0To1
BronchitisSeverity SEScalar0To1

Chronic Pericardial Effusion

Pericardial effusion ("fluid around the heart") is an abnormal accumulation of fluid in the pericardial cavity. Because of the limited amount of space in the pericardial cavity, fluid accumulation leads to an increased intrapericardial pressure which can negatively affect heart function. A pericardial effusion with enough pressure to adversely affect heart function is called cardiac tamponade. Pericardial effusion usually results from a disturbed equilibrium between the production andre-absorption of pericardial fluid, or from a structural abnormality that allows fluid to enter the pericardial cavity. Normal levels of pericardial fluid are from 15 to 50 mL.

Property Name Type Definition
AccumulatedVolume SEScalarVolume The amount of fluid in the pericardial cavity.

Consume Meal

Consume nutrients into the body along with a time elapsed since this meal.

Property Name Type Definition
Meal SEMeal MealTable
MealFile String File containing a meal objet with properties to initialize the system with.

Chronic Renal Stenosis

Narrowing of the renal artery.

Property Name Type Definition
LeftKidneySeverity SEScalar0To1 Fraction of the Left kidney artery stenosed.
RightKidneySeverity SEScalar0To1 Fraction of the Right kidney artery stenosed.

Chronic Ventricular Systolic Dysfunction

Impairment of the ventricular contraction, reducing the ability of the heart to pump blood.

Lobar Pneumonia

Lobar pneumonia is a form of pneumonia that affects one or more lobes of the lungs. As fluid fills portions of the lung it becomes more difficult to breath and the gas diffusion surface area in the alveoli is reduced.

Property Name Type Definition
LeftLungAffected SEScalar0To1 Fraction of the Left Lung Affected.
Severity SEScalar0To1
RightLungAffected SEScalar0To1 Fraction of the Left Lung Affected.

Impaired Alveolar Exchange

Generic way to specify the effectivness of alveolar exchange.

Property Name Type Definition
ImpairedSurfaceArea SEScalarArea Surface Area of the impaired alveoli.
ImpairedFraction SEScalar0To1 Surface Area Fraction of the impaired alveoli.

Chronic Anemia

Condition characterized by reduced red blood cells, which leads to reduced oxygen carrying capacity. Implemented by reducing the amount of hemoglobin in the blood.

Property Name Type Definition
ReductionFactor SEScalar0To1 The fraction to reduce the amount of hemoglobin by.

Urinalysis

Property Name Type Definition
Glucose ePresenceIndicator Glucose is normally not present in urine. When glucose is present, the condition is called glucosuria.
Blood ePresenceIndicator This test is used to detect hemoglobin in the urine (hemoglobinuria). Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). Its presence in the urine indicates blood in the urine (known as hematuria).
Ketone ePresenceIndicator Ketones are not normally found in the urine. They are intermediate products of fat metabolism. They can form when a person does process enough carbohydrates.
Nitrite ePresenceIndicator This test detects nitrite and is based upon the fact that many bacteria can convert nitrate to nitrite in the urine.
SpecificGravity SEScalar A measure of urine concentration that can be determined using a chemical test.
Urobilinogen SEScalarMassPerVolume Urobilinogen is normally present in urine in low concentrations. It is formed in the intestine from bilirubin, and a portion of it is absorbed back into the bloodstream.
Appearance eClarityIndicator Clarity of the urine.
LeukocyteEsterase ePresenceIndicator Leukocyte esterase is an enzyme present in most white blood cells (WBCs). Normally, a few white blood cells (see microscopic examination) are present in urine and this test is negative. When the number of WBCs in urine increases significantly, this screening test will become positive.
Protein ePresenceIndicator The protein test pad measures the amount of albumin in the urine. Normally, there will not be detectable quantities.
Color eUrineColor Color of the urine.
PH SEScalar
Bilirubin SEScalar Bilirubin is not present in the urine of normal, healthy individuals. Bilirubin is a waste product that is produced by the liver from the hemoglobin of RBCs that are removed from circulation.

Comprehensive Metabolic Panel

Property Name Type Definition
Calcium SEScalarMassPerVolume About half of the calcium in the blood is attached to proteins, mainly albumin. For this reason, the calcium blood test can be misleading, and sometimes needs tests to confirm the result.
Potassium SEScalarAmountPerVolume Measures the amount of potassium in the fluid portion (serum) of the blood. Potassium (K+) helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells.
Glucose SEScalarMassPerVolume Measures the amount of a sugar called glucose in a sample of your blood.
BUN SEScalarMassPerVolume BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down.
Sodium SEScalarAmountPerVolume Measures the amount of sodium in the blood.
AST SEScalarMassPerVolume AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.
Chloride SEScalarAmountPerVolume Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance.
Creatinine SEScalarMassPerVolume Measures the level of creatinine in the blood. This test is done to see how well your kidneys work.
Albumin SEScalarMassPerVolume Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.
TotalProtein SEScalarMassPerVolume Measures the total amount of two classes of proteins found in the fluid portion of your blood. These are albumin and globulin.
CO2 SEScalarAmountPerVolume Most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.
ALT SEScalarMassPerVolume Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.
TotalBilirubin SEScalarMassPerVolume Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.
ALP SEScalarMassPerVolume Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Complete Blood Count

Property Name Type Definition
WhiteBloodCellCount SEScalarAmountPerVolume Number of white blood cells per volume of blood.
MeanCorpuscularHemoglobin SEScalarMassPerAmount (MCH) Hemoglobin amount per red blood cell.
Hematocrit SEScalar0To1 Volume percentage of red blood cells in the blood.
RedBloodCellCount SEScalarAmountPerVolume Number of red blood cells per volume of blood.
PlateletCount SEScalarAmountPerVolume Number of platelets per volume of blood.
MeanCorpuscularHemoglobinConcentration SEScalarMassPerVolume (MCHC) The amount of hemoglobin relative to the size of the cell (hemoglobin concentration) per red blood cell.
Hemoglobin SEScalarMassPerVolume The concentration of hemoglobin in the blood.
MeanCorpuscularVolume SEScalarVolume (MCV) Average red blood cell size.

Pulmonary Function Test

A group of tests that measure how well the lungs take in and release air, and how well they move gases from the atmosphere into the body's circulation.

Property Name Type Definition
ForcedExpiratoryFlow SEScalarVolumePerTime Measures air flow halfway through an exhale.
ForcedExpiratoryVolume SEScalarVolume The amount of air which can be exhaled with force in one breath.
LungVolumePlot SEFunctionVolumeVsTime The lung volume as a function of time from the pulmonary function test.
ForcedVitalCapacity SEScalarVolume The amount of air which can be forcibly exhaled from the lungs after taking the deepest possible breath.
ResidualVolume SEScalarVolume The amount of air in the lungs after the patient has exhaled completely.
FunctionalResidualCapacity SEScalarVolume The volume of air in the lungs at the end of a normal exhaled breath.
InspiratoryReserveVolume SEScalarVolume The difference between the maximum lung volume and the volume at the end of a normal inhalation.
SlowVitalCapacity SEScalarVolume The amount of air that can be exhaled slowly after the deepest possible inhalation.
ExpiratoryReserveVolume SEScalarVolume Difference between the amount of air in the lungs after a normal exhale and the amount after an exhale with force.
VitalCapacity SEScalarVolume The volume of air that can be exhaled from the lungs after the deepest possible inhalation.
InspiratoryCapacity SEScalarVolume The difference between the maximum lung capacity and the volume at the end of a normal tidal volume exhalation.
MaximumVoluntaryVentilation SEScalarVolume The amount of air that can be breathed in and out during 1 minute.
PeakExpiratoryFlow SEScalarVolumePerTime Air flow during forced exhale of the deepest possible breath.
TotalLungCapacity SEScalarVolume The volume of air in the lungs after the deepest possible inhalation.

Meal

Specify an amount of time to digest the specified nutrition information.

Property Name Type Definition
Calcium SEScalarMass
ElapsedTime SEScalarTime
FatDigestionRate SEScalarMassPerTime
Sodium SEScalarMass
Protein SEScalarMass
CarbohydrateDigestionRate SEScalarMassPerTime
Water SEScalarVolume
Fat SEScalarMass
Carbohydrate SEScalarMass
ProteinDigestionRate SEScalarMassPerTime

Nutrition

Nutritional information for eating.

Property Name Type Definition
Calcium SEScalarMass
FatDigestionRate SEScalarMassPerTime
Sodium SEScalarMass
Protein SEScalarMass
CarbohydrateDigestionRate SEScalarMassPerTime
Water SEScalarVolume
Fat SEScalarMass
Carbohydrate SEScalarMass
ProteinDigestionRate SEScalarMassPerTime

%

Environmental Conditions

Property Name Type Definition
ClothingResistance SEScalarHeatResistanceArea
AirVelocity SEScalarLengthPerTime
AmbientGas List of SESubstanceFractionAmountSubstanceFractionAmountTable
AmbientTemperature SEScalarTemperature
RelativeHumidity SEScalar0To1
AmbientAerosol List of SESubstanceConcentrationSubstanceConcentrationTable
Emissivity SEScalar0To1
AtmosphericPressure SEScalarPressure
SurroundingType eSurroundingType
AirDensity SEScalarMassPerVolume
MeanRadiantTemperature SEScalarTemperature
RespirationAmbientTemperature SEScalarTemperature

Active Conditioning

Property Name Type Definition
Power SEScalarPower
SurfaceAreaFraction SEScalar0To1
SurfaceArea SEScalarArea

%

Applied Temperature

Property Name Type Definition
SurfaceAreaFraction SEScalar0To1
Temperature SEScalarTemperature
SurfaceArea SEScalarArea

Environment

Property Name Type Definition
ActiveCooling SEActiveConditioning ActiveConditioningTable
EvaporativeHeatLoss SEScalarPower Total patient heat loss due to evaporation.
ConvectiveHeatTranferCoefficient SEScalarHeatConductancePerArea The proportionality coefficient between the heat flux and the thermodynamic driving force for the flow of heat due to convection.
EvaporativeHeatTranferCoefficient SEScalarHeatConductancePerArea The proportionality coefficient between the heat flux and the thermodynamic driving force for the flow of heat due to evaporation.
AppliedTemperature SEAppliedTemperature AppliedTemperatureTable
ActiveHeating SEActiveConditioning ActiveConditioningTable
RespirationHeatLoss SEScalarPower Total heat loss from the Respiratory System.
RadiativeHeatLoss SEScalarPower Total patient heat loss due to radiation.
RadiativeHeatTranferCoefficient SEScalarHeatConductancePerArea The proportionality coefficient between the heat flux and the thermodynamic driving force for the flow of heat due to radiation.
ConvectiveHeatLoss SEScalarPower Total patient heat loss due to convection.
Conditions SEEnvironmentalConditions EnvironmentalConditionsTable
SkinHeatLoss SEScalarPower Total heat loss from the Respiratory skin.

%

%

Thermal Application

Create an external heat source.

Property Name Type Definition
ActiveCooling SEActiveConditioning ActiveConditioningTable
AppliedTemperature SEAppliedTemperature AppliedTemperatureTable
ActiveHeating SEActiveConditioning ActiveConditioningTable

Change Environment Conditions

The environment conditions to change.

Property Name Type Definition
ConditionsFile String File containing an environment conditions objet with properties to set in the environmental conditions.
Conditions SEEnvironmentalConditions EnvironmentalConditionsTable

Initial Environment Conditions

The configuration of the environment to use during stabilization.

Property Name Type Definition
ConditionsFile String File containing an environment conditions objet with properties to set in the environmental conditions.
Conditions SEEnvironmentalConditions EnvironmentalConditionsTable

AnesthesiaeEvent

Property Name Type Definition
OxygenBottleOneExhausted eEvent
OxygenBottleTwoExhausted eEvent
ReliefValveActive eEvent
UNRECOGNIZED eEvent

%

Anesthesia Machine Chamber

Property Name Type Definition
Substance SESubstance SubstanceTable
SubstanceFraction SEScalar0To1

Anesthesia Machine

Property Name Type Definition
Connection eConnection
PositiveEndExpiredPressure SEScalarPressure The pressure above atmospheric pressure that exists in the lungs at the end of expiration.
OxygenSource eOxygenSource
ReliefValvePressure SEScalarPressure Pressure at while the valve opens to prevent a build up of pressure in the system.
OxygenBottleTwo SEAnesthesiaMachineOxygenBottle AnesthesiaMachineOxygenBottleTable
OxygenFraction SEScalar0To1 The fraction of the fresh gas inlet flow that is oxygen.
InspiratoryExpiratoryRatio SEScalar The ratio of time spent in the inspiratory phase vs the expiratory phase of respiration.
VentilatorPressure SEScalarPressure The pressure of the ventilator.
LeftChamber SEAnesthesiaMachineChamber AnesthesiaMachineChamberTable
PrimaryGas ePrimaryGas
OxygenBottleOne SEAnesthesiaMachineOxygenBottle AnesthesiaMachineOxygenBottleTable
RespiratoryRate SEScalarFrequency The prescribed rate of positive-pressure ventilation.
InletFlow SEScalarVolumePerTime The total fresh gas inlet flow.
RightChamber SEAnesthesiaMachineChamber AnesthesiaMachineChamberTable

%

Anesthesia Machine Oxygen Bottle

Property Name Type Definition
Volume SEScalarVolume

Oxygen Tank Pressure Loss

The active oxygen tank losses pressure.

Ventilator Pressure Loss

The ventilator losses pressure.

Property Name Type Definition
Severity SEScalar0To1 Severity of the loss from 0 to 1.

Soda Lime Failure

A soda lime failure.

Property Name Type Definition
Severity SEScalar0To1 Severity of the failure from 0 to 1.

Oxygen Wall Port Pressure Loss

The wall port losses oxygen pressure.

Inspiratory Valve Leak

A leak in the inspiratory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

Expiratory Valve Leak

A leak in the expiritory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

Vaporizer Failure

The vaporizer fails.

Property Name Type Definition
Severity SEScalar0To1 Severity of the failure from 0 to 1.

Y Piece Disconnect

The Y Piece becomes disconnected.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

Mask Leak

A leak in the mask.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

Anesthesia Machine Configuration

The configuration of the anesthesia machine to use.

Property Name Type Definition
Configuration SEAnesthesiaMachine AnesthesiaMachineTable
ConfigurationFile String File containing an anesthesia machine objet with properties to set in the system anesthesia machine.

Tube Cuff Leak

A leak in the tube cuff.

Property Name Type Definition
Severity SEScalar0To1 Severity of the leak from 0 to 1.

Inspiratory Valve Obstruction

An obstruction in the inspiritory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the obstruction from 0 to 1.

Expiratory Valve Obstruction

An obstruction in the expiritory valve.

Property Name Type Definition
Severity SEScalar0To1 Severity of the obstruction from 0 to 1.

Electro Cardio Gram Waveform

The amount of electric potential given off by lead 12 of the ECG.

Property Name Type Definition
Lead eLead Lead number of the waveform provided.
TimeStep SEScalarTime Time step of the data provided.
Data SEFunctionElectricPotentialVsTime Dataset of a full heart cycle.
Rhythm eHeartRhythm Rhythm type of the waveform provided.

Electro Cardio Gram

Generic ECG machine to assess the heart rhythm.

Property Name Type Definition
Lead3ElectricPotential SEScalarElectricPotential The amount of electric potential given off by lead 3 of the ECG.

Electro Cardio Gram Waveform List

Active indicies of the WaveForm Data used to interpolate the current electric potential.

%

Inhaler

Generic inhaler for substance administration.

Property Name Type Definition
MeteredDose SEScalarMass Dosage of substance.
SpacerVolume SEScalarVolume Volume of a spacer, if used.
Substance SESubstance SubstanceTable
NozzleLoss SEScalar0To1 Fraction of substance lost from the inhaler. -.

%

Inhaler Configuration

The configuration of the inhaler to use.

Property Name Type Definition
Configuration SEInhaler InhalerTable
ConfigurationFile String File containing an inhaler objet with properties to set in the system inhaler.

Drug System

Property Name Type Definition
BronchodilationLevel SEScalarNegative1To1
SedationLevel SEScalar0To1
NeuromuscularBlockLevel SEScalar0To1
PulsePressureChange SEScalarPressure
TubularPermeabilityChange SEScalarNegative1To1
MeanBloodPressureChange SEScalarPressure
HeartRateChange SEScalarFrequency
TidalVolumeChange SEScalarVolume
PupillaryResponse SEPupillaryResponse PupillaryResponseTable
RespirationRateChange SEScalarFrequency

Blood Chemistry System

Property Name Type Definition
RedBloodCellCount SEScalarAmountPerVolume Total number of red blood cells in the blood.
BloodPH SEScalar Measure of acidity or basicity of the blood.
VenousOxygenPressure SEScalarPressure Partial pressure of oxygen in the vena cava.
ShuntFraction SEScalar0To1 Fraction of the blood flow that bypasses the alveoli; therefore, does not engage is gas exchange.
VolumeFractionNeutralPhospholipidInPlasma SEScalar0To1 Fraction of the plasma that is made up of neutral phospholipids.
BloodUreaNitrogenConcentration SEScalarMassPerVolume The BUN concentration in the blood.
CarbonMonoxideSaturation SEScalar0To1 The fraction of hemoglobin that is carbon monoxide bound.
PulseOximetry SEScalar0To1 The fraction of hemoglobin with bound oxygen as measured optically, which can include Carbon Monoxide.
PulmonaryArterialCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the pulmonary arteries.
StrongIonDifference SEScalarAmountPerVolume Difference between the positive and negative strong ion concentrations in the blood.
TotalProteinConcentration SEScalarMassPerVolume The concentration of urea in the blood.
VenousCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the vena cava.
VolumeFractionNeutralLipidInPlasma SEScalar0To1 Fraction of the plasma that is made up of neutral lipids.
PulmonaryVenousOxygenPressure SEScalarPressure Partial pressure of oxygen in the pulmonary veins.
ArterialCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the aorta.
BloodDensity SEScalarMassPerVolume Mass per unit volume of the blood.
HemoglobinContent SEScalarMass The total amount of hemoglobin in the blood.
PulmonaryVenousCarbonDioxidePressure SEScalarPressure Partial pressure of carbon dioxide in the pulmonary veins.
CarbonDioxideSaturation SEScalar0To1 The fraction of hemoglobin that is carbon dioxide bound.
Phosphate SEScalarAmountPerVolume Sum of all inorganic phosphate in the blood.
WhiteBloodCellCount SEScalarAmountPerVolume Total number of white blood cells in the blood.
Hematocrit SEScalar0To1 Volume percentage of red blood cells in the blood.
OxygenSaturation SEScalar0To1 The fraction of hemoglobin that is oxygen bound.
PulmonaryArterialOxygenPressure SEScalarPressure Partial pressure of oxygen in the pulmonary arteries.
PlasmaVolume SEScalarVolume Volume of the plasma.
ArterialOxygenPressure SEScalarPressure Partial pressure of oxygen in the aorta.
BloodSpecificHeat SEScalarHeatCapacitancePerMass The amount of energy required to raise one kilogram of blood by one degree Celsius.

Endocrine System

Property Name Type Definition
InsulinSynthesisRate SEScalarAmountPerTime Insulin production rate.

Gastrointestinal System

Property Name Type Definition
StomachContents SENutrition NutritionTable
ChymeAbsorptionRate SEScalarVolumePerTime Rate of the absorption of nutrients from chyme into the blood stream.

Renal System

Property Name Type Definition
LeftReabsorptionFiltrationCoefficient SEScalarVolumePerTimePressure Value which determines how much of a substance is reabsorbed into the blood stream in the left Kidney.
LeftPeritubularCapillariesHydrostaticPressure SEScalarPressure Pressure generated by the fluid in the peritubular capillaries in the left Kidney.
RenalBloodFlow SEScalarVolumePerTime Blood flow into the kidney that is not filtered into the tubules.
RightGlomerularFluidPermeability SEScalarVolumePerTimePressureArea Permeability coeffitient of the capillary tissue in the left Kidney.
LeftGlomerularFiltrationCoefficient SEScalarVolumePerTimePressure Calculated for each substance to determine ease of transport into the tubules in the left Kidney.
LeftGlomerularFiltrationRate SEScalarVolumePerTime Flow rate of filtrate into the tubules in left Kidney.
LeftGlomerularFluidPermeability SEScalarVolumePerTimePressureArea Permeability coeffitient of the capillary tissue in the left Kidney.
LeftTubularHydrostaticPressure SEScalarPressure Preassure generated by the fluid in the tubules in the left Kidney.
LeftFiltrationFraction SEScalar0To1 Scalar used to compute reabsorption for substances in left Kidney.
RenalPlasmaFlow SEScalarVolumePerTime Plasma flow into the kidney that is not filtered into the tubules.
LeftAfferentArterioleResistance SEScalarFlowResistance resistance to flow going into the glomerular capillaries in the left Kidney
LeftReabsorptionRate SEScalarVolumePerTime Rate at which fluid or a substance is transported into the peritubular capillaries in the left Kidney.
RightFiltrationFraction SEScalar0To1 Scalar used to compute reabsorption for substances in left Kidney.
RightPeritubularCapillariesHydrostaticPressure SEScalarPressure Pressure generated by the fluid in the peritubular capillaries in the left Kidney.
RightAfferentArterioleResistance SEScalarFlowResistance resistance to flow going into the glomerular capillaries in the right Kidney
UrineOsmolality SEScalarOsmolality The osmolar pressure contributions of the sodium, urea and glucose divided by the mass of the fluid.
GlomerularFiltrationRate SEScalarVolumePerTime Flow rate of filtrate into the tubules.
LeftNetReabsorptionPressure SEScalarPressure Total pressure directed into the peritubular capillaries in the left Kidney.
RenalVascularResistance SEScalarFlowResistance Total resistance o f the kidney vasculature.
RightTubularReabsorptionFiltrationSurfaceArea SEScalarArea Surface ares of the tubules which is subject to fluid transport (reabsorption) in the left Kidney.
LeftTubularOsmoticPressure SEScalarPressure Pressure generated by substances in the tubules in the left Kidney.
LeftBowmansCapsulesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the bowmans capsules in the left Kidney.
RightBowmansCapsulesOsmoticPressure SEScalarPressure Pressure generated from substances in the bowmans capsules in the right Kidney.
RightTubularHydrostaticPressure SEScalarPressure Preassure generated by the fluid in the tubules in the left Kidney.
UrineOsmolarity SEScalarOsmolarity The osmolar pressure contributions of the sodium, urea and glucose divided by the volume of the fluid.
LeftGlomerularCapillariesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the glomerular capillaries in the left Kidney.
RightNetReabsorptionPressure SEScalarPressure Total pressure directed into the peritubular capillaries in the left Kidney.
RightGlomerularFiltrationSurfaceArea SEScalarArea Surface area of glomerular capillaries that experiance filtration in the left Kidney.
LeftTubularReabsorptionFluidPermeability SEScalarVolumePerTimePressureArea Permeability of the tissue in the tubules, influencing resistance to flow into peritubular capillaries in the left Kidney.
LeftBowmansCapsulesOsmoticPressure SEScalarPressure Pressure generated from substances in the bowmans capsules in the left Kidney.
RightNetFiltrationPressure SEScalarPressure Total pressure directed into the tubules in the left Kidney.
FiltrationFraction SEScalar0To1 Scalar used to compute reabsorption for substances.
RightGlomerularFiltrationCoefficient SEScalarVolumePerTimePressure Calculated for each substance to determine ease of transport into the tubules in the left Kidney.
RightTubularOsmoticPressure SEScalarPressure Pressure generated by substances in the tubules in the left Kidney.
RightPeritubularCapillariesOsmoticPressure SEScalarPressure Pressure generated by the substance concentration in the peritubular capillaries in the left Kidney.
LeftPeritubularCapillariesOsmoticPressure SEScalarPressure Pressure generated by the substance concentration in the peritubular capillaries in the left Kidney.
LeftTubularReabsorptionFiltrationSurfaceArea SEScalarArea Surface ares of the tubules which is subject to fluid transport (reabsorption) in the left Kidney.
UrinationRate SEScalarVolumePerTime Rate that fluid exits the bladder.
UrineUreaNitrogenConcentration SEScalarMassPerVolume Scaled concentration of Urea in the bladder.
RightGlomerularCapillariesOsmoticPressure SEScalarPressure Pressure generated from substances in the capillaries in the left Kidney.
RightGlomerularFiltrationRate SEScalarVolumePerTime Flow rate of filtrate into the tubules in left Kidney.
RightTubularReabsorptionFluidPermeability SEScalarVolumePerTimePressureArea Permeability of the tissue in the tubules, influencing resistance to flow into peritubular capillaries in the left Kidney.
UrineVolume SEScalarVolume The volume of the urine in the bladder.
LeftNetFiltrationPressure SEScalarPressure Total pressure directed into the tubules in the left Kidney.
RightReabsorptionRate SEScalarVolumePerTime Rate at which fluid or a substance is transported into the peritubular capillaries in the left Kidney.
UrineProductionRate SEScalarVolumePerTime The rate of fluid flow to the bladder.
LeftGlomerularFiltrationSurfaceArea SEScalarArea Surface area of glomerular capillaries that experiance filtration in the left Kidney.
RightReabsorptionFiltrationCoefficient SEScalarVolumePerTimePressure Value which determines how much of a substance is reabsorbed into the blood stream in the left Kidney.
LeftGlomerularCapillariesOsmoticPressure SEScalarPressure Pressure generated from substances in the capillaries in the left Kidney.
RightBowmansCapsulesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the bowmans capsules in the right Kidney.
UrineSpecificGravity SEScalar The density of the fluid relative to water.
RightGlomerularCapillariesHydrostaticPressure SEScalarPressure Pressure generated from fluid in the glomerular capillaries in the left Kidney.
LeftEfferentArterioleResistance SEScalarFlowResistance Resistance to flow into the peritubular capillaries in the left Kidney.
RightEfferentArterioleResistance SEScalarFlowResistance Resistance to flow into the peritubular capillaries in the left Kidney.

Nervous System

Property Name Type Definition
BaroreceptorHeartElastanceScale SEScalar Heart elastance multiplier used to scale the heart rate due to baroreceptor feedback.
ChemoreceptorHeartRateScale SEScalar Heart rate multiplier used to scale the heart rate due to baroreceptor feedback.
BaroreceptorHeartRateScale SEScalar Heart rate multiplier used to scale the heart rate due to baroreceptor feedback.
BaroreceptorResistanceScale SEScalar Cardiovascular resistance multiplier used to scale the heart rate due to baroreceptor feedback.
ChemoreceptorHeartElastanceScale SEScalar Heart elastance multiplier used to scale the heart rate due to baroreceptor feedback.
LeftEyePupillaryResponse SEPupillaryResponse PupillaryResponseTable
RightEyePupillaryResponse SEPupillaryResponse PupillaryResponseTable
BaroreceptorComplianceScale SEScalar Cardiovascular compliance multiplier used to scale the heart rate due to baroreceptor feedback.

Hepatic System

Tissue System

Provides data pertaining to the extracellular and intracelluar space.

Property Name Type Definition
IntracellularFluidPH SEScalar The acidity or alkalinity of the extravascular intercellular fluid.
RespiratoryExchangeRatio SEScalar The true ratio of carbon dioxide produced to oxygen consumed.
ExtracellularFluidVolume SEScalarVolume Volume of fluid outside of cells AND outside of the blood vessels.
IntracellularFluidVolume SEScalarVolume Volume of fluid in the cells outside of the blood vessels.
CarbonDioxideProductionRate SEScalarVolumePerTime The carbon dioxide generated on the tissue level from aerobic metabolism.
ExtravascularFluidVolume SEScalarVolume Total fluid volume outside of the blood vessels.
OxygenConsumptionRate SEScalarVolumePerTime The oxygen consumed on the tissue level from aerobic metabolism.

Cardiovascular System

Property Name Type Definition
ArterialPressure SEScalarPressure The current arteial pressure.
PulmonaryMeanShuntFlow SEScalarVolumePerTime The average blood flow diverted from the pulmonary capillaries (not oxygenated) over the course of a cardiac cycle.
MeanArterialPressure SEScalarPressure The average arterial pressure throughout each cardiac cycle.
PulmonarySystolicArterialPressure SEScalarPressure The maximum pressure in the pulmonary arteries over the course of a cardiac cycle.
PulmonaryVascularResistance SEScalarFlowResistance The resistance offered by the pulmonary circulation.
HeartEjectionFraction SEScalar0To1 The current pressure in the aorta.
CardiacOutput SEScalarVolumePerTime The volume of blood being pumped from the heart in a given time interval.
It is defined as the heart rate multiplied by the stroke volume.
PulmonaryMeanCapillaryFlow SEScalarVolumePerTime The average blood flow in the pulmonary capillaries over the course of a cardiac cycle.
IntracranialPressure SEScalarPressure The pressure inside the skull. Equal to the cerebral blood pressure with the cerebrospinal fluid pressure being assumed equal.
PulmonaryCapillariesWedgePressure SEScalarPressure The pressure within the pulmonary capillaries.
PulmonaryDiastolicArterialPressure SEScalarPressure The minimum pressure that occurs in the pulmonary arteries over the course of a cardiac cycle.
HeartRhythm eHeartRhythm Current heart rhythm.
MeanArterialCarbonDioxidePartialPressureDelta SEScalarPressure The change of the the mean of the partial pressure of carbon dioxide in the aorta from the previous cardiac cycle.
CerebralPerfusionPressure SEScalarPressure The difference between the mean arterial pressure and the cerebral blood pressure. Defines the hydrostatic diffusion gradient.
PulmonaryMeanArterialPressure SEScalarPressure The average pressure that occurs in the pulmonary arteries over the course of a cardiac cycle.
CardiacIndex SEScalarVolumePerTimeArea Relates heart performance to the size of the individual.
HeartStrokeVolume SEScalarVolume The volume of blood pumped from the left ventricle in one contraction.
MeanArterialCarbonDioxidePartialPressure SEScalarPressure The mean of the partial pressure of carbon dioxide in the aorta over a cardiac cycle.
MeanCentralVenousPressure SEScalarPressure The average pressure in the vena cava over the course of a cardiac cycle.
SystemicVascularResistance SEScalarFlowResistance The resistance to blood flow through the entire systemic vasculature, not including the pulmonary circulation.
PulmonaryArterialPressure SEScalarPressure The current pressure in the pulmonary arteries.
PulmonaryVascularResistanceIndex SEScalarPressureTimePerVolumeArea Relates pulmonary circulation performance to the size of the individual.
CerebralBloodFlow SEScalarVolumePerTime The rate of blood flow into the skull, thus supplying the brain.
DiastolicArterialPressure SEScalarPressure The minimum pressure in the aorta over the course of a cardiac cycle.
MeanSkinFlow SEScalarVolumePerTime The blood flow to the skin averaged over the current cardiac cycle time.
PulsePressure SEScalarPressure The difference between the systolic and diastolic pressures.
BloodVolume SEScalarVolume The total volume of fluid within the cardiovascular system.
SystolicArterialPressure SEScalarPressure The maximum pressure in the aorta over the course of a cardiac cycle.
HeartRate SEScalarFrequency The fraction of the blood that is pumped out of the ventricle during a cardiac cycle.
CentralVenousPressure SEScalarPressure The instantaneous pressure of the venus return.

Energy System

Property Name Type Definition
CreatinineProductionRate SEScalarAmountPerTime The generation of creatinine in the muscle tissue per.
TotalMetabolicRate SEScalarPower The basal metabolic rate plus additional energy expenditure rates due to activity.
LactateProductionRate SEScalarAmountPerTime The molar amount of lactate generated on the tissue level from anaerobic metabolism.
SweatRate SEScalarMassPerTime Mass of sweat generated per unit time due to elevated core temperature.
ExerciseMeanArterialPressureDelta SEScalarPressure The pressure delta that occurs during exercise. Used to modify the baroreceptor set-point.
FatigueLevel SEScalar0To1 The exhaustion level of the body, or inability to perform physical exercise.
KetoneProductionRate SEScalarAmountPerTime The molar amount of ketones generated in the liver.
AchievedExerciseLevel SEScalar0To1 The fraction of how much of the requested exercise the patient is able to achieve. 1.0 means the the patient is performing at the requested level. Nan is the patient is not exercising (no Action)
SkinTemperature SEScalarTemperature The skin surface temperature.
TotalWorkRateLevel SEScalar0To1 The current patient work rate above basal over the maximum work rate capable by the patient.
CoreTemperature SEScalarTemperature The internal body temperature.

Physiology System

Pupillary Response

Property Name Type Definition
ReactivityModifier SEScalarNegative1To1 Change in pupil recation time -1 complete reduction/no response, 0 is normal, and 1 is the fastest reaction time.
SizeModifier SEScalarNegative1To1 Pupil size change from normal. -1 is fully constricted, 0 is no change, +1 is fully dilated.
ShapeModifier SEScalarNegative1To1 Percentage change in pupil shape from normal. Positive is vertical ovoid. Negative is horizontal ovoid.

Respiratory System

Property Name Type Definition
TotalDeadSpaceVentilation SEScalarVolumePerTime The air flow to the dead space.
ExpiratoryFlow SEScalarVolumePerTime Instantaneous airflow out of the lungs (negative value when inhaling)
EndTidalCarbonDioxideFraction SEScalar0To1 The fraction of CarbonDioxide in the trachea that is carbon dioxide at the end of each respiratory cycle.
EndTidalCarbonDioxidePressure SEScalarPressure The pressure of CarbonDioxide in the trachea that is carbon dioxide at the end of each respiratory cycle.
TidalVolume SEScalarVolume The volume of air moved into or out of the lungs during normal respiration.
TotalPulmonaryVentilation SEScalarVolumePerTime The flow rate representing the exchange of air between the lungs and ambient air.
PulmonaryCompliance SEScalarFlowCompliance The total compliance of the lungs.
InspiratoryFlow SEScalarVolumePerTime TInstantaneous airflow into the lungs (negative value when exhaling).
TotalAlveolarVentilation SEScalarVolumePerTime The air flow to the alveoli.
PulmonaryResistance SEScalarFlowResistance The total resistance to airflow through the lungs.
SpecificVentilation SEScalar The ratio of the volume of gas entering a region of the lung following an inspiration and the end-expiratory volume of that same lung region.
RespirationDriverPressure SEScalarPressure Pressure that drives the respiratory system in generating physiologic pressures.
InspiratoryExpiratoryRatio SEScalar The ratio of the length of time of inspiration to the length of time of expiration.
TotalLungVolume SEScalarVolume The total volume of air within the lungs at any given time.
AlveolarArterialGradient SEScalarPressure Measure of the difference between the alveolar concentration of oxygen and the arterial concentration of oxygen to assess the integrity of the alveolar capillary unit..
RespirationRate SEScalarFrequency The frequency of the respiratory cycle.
TranspulmonaryPressure SEScalarPressure The pressure difference between the alveoli and the intrapleural space.
CarricoIndex SEScalarPressure The ratio of arterial partial pressure O2 and the inspired O2. O2 level in blood vs. Concentration of O2 in a breath.
RespirationMusclePressure SEScalarPressure Combined driver pressure of the muscles that contribute to inhalation and exhalation, by aiding in the expansion and contraction of the thoracic cavity.

Substance

Property Name Type Definition
Name String
RelativeDiffusionCoefficient SEScalar
SystemicMassCleared SEScalarMass
MassInBlood SEScalarMass
DiffusingCapacity SEScalarVolumePerTimePressure
EndTidalFraction SEScalar0To1
EndTidalPressure SEScalarPressure
MolarMass SEScalarMassPerAmount
PlasmaConcentration SEScalarMassPerVolume
Aerosolization SESubstanceAerosolization SubstanceAerosolizationTable
Density SEScalarMassPerVolume
PD SESubstancePharmacodynamics SubstancePharmacodynamicsTable
Clearance SESubstanceClearance SubstanceClearanceTable
MassInBody SEScalarMass
MassInTissue SEScalarMass
State eState
MaximumDiffusionFlux SEScalarMassPerAreaTime
SolubilityCoefficient SEScalarInversePressure
TissueConcentration SEScalarMassPerVolume
PK SESubstancePharmacokinetics SubstancePharmacokineticsTable
MichaelisCoefficient SEScalar
AlveolarTransfer SEScalarVolumePerTime
BloodConcentration SEScalarMassPerVolume

Substance Tissue Pharmacokinetics

Property Name Type Definition
Name String
PartitionCoefficient SEScalar

Substance Quantity

Basic Substance Quantity.

Substance Pharmacokinetics

Property Name Type Definition
Physicochemicals SESubstancePhysicochemicals SubstancePhysicochemicalsTable
TissueKinetics Collection CollectionTable

Liquid Substance Quantity

The quantity of a solid,liquid, or gas substance in a liquid compartment.

Property Name Type Definition
MassExcreted SEScalarMass The total mass of a substance excreted in the specified compartment.
MassCleared SEScalarMass The total mass of a substance cleared in the specified compartment.
MassDeposited SEScalarMass The total mass of a substance deposited on the wall of the compartment.
Mass SEScalarMass The total mass of a substance in the specified compartment.
Molarity SEScalarAmountPerVolume The molarity of a substance in the specified compartment.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Saturation SEScalar0To1 The saturation of a substance in the specified compartment. (if applicable, like O2 and CO2)
Concentration SEScalarMassPerVolume The concentration of a substance in the specified compartment.

Substance Physicochemicals

Property Name Type Definition
LogP SEScalar
AcidDissociationConstant SEScalar
IonicState eIonicState
BindingProtein eBindingProtein
FractionUnboundInPlasma SEScalar0To1
OralAbsorptionRateConstant SEScalar
BloodPlasmaRatio SEScalar

Gas Substance Quantity

The quantity of a gas substance in a gas compartment.

Property Name Type Definition
VolumeFraction SEScalar0To1 The amount of a substcane in the specified comparment as a fraction of all substance volume.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Volume SEScalarVolume The total volume of a substance in the specified compartment.

Substance Fraction Amount

Property Name Type Definition
Amount SEScalar0To1
Substance SESubstance SubstanceTable

Substance Pharmacodynamics

Property Name Type Definition
EC50 SEScalarMassPerVolume
NeuromuscularBlock SEScalarNegative1To1
EMaxShapeParameter SEScalar
TidalVolumeModifier SEScalarNegative1To1
PupillaryResponse SEPupillaryResponse PupillaryResponseTable
Sedation SEScalarNegative1To1
TubularPermeabilityModifier SEScalarNegative1To1
RespirationRateModifier SEScalarNegative1To1
DiastolicPressureModifier SEScalarNegative1To1
HeartRateModifier SEScalarNegative1To1
SystolicPressureModifier SEScalarNegative1To1
Bronchodilation SEScalarNegative1To1

Substance Compound

Property Name Type Definition
Name String
Components List of SESubstanceCompoundComponentSubstanceCompoundComponentTable

Substance Manager

Substance Clearance

Property Name Type Definition
RenalReabsorptionRate SEScalarMassPerTime
RenalTransportMaximum SEScalarMassPerTime
RenalExcretionRate SEScalarMassPerTime
RenalFiltrationRate SEScalarMassPerTime
FractionMetabolizedInGut SEScalar0To1
FractionUnboundInPlasma SEScalar0To1
ChargeInBlood eCharge
FractionExcretedInFeces SEScalar0To1
IntrinsicClearance SEScalarVolumePerTimeMass
RenalClearance SEScalarVolumePerTimeMass
SystemicClearance SEScalarVolumePerTimeMass
RenalReabsorptionRatio SEScalar
FractionExcretedInUrine SEScalar0To1
GlomerularFilterability SEScalar

Substance Aerosolization

Property Name Type Definition
BronchioleModifier SEScalarNegative1To1
ParticulateSizeDistribution SEHistogramFractionVsLength
InflammationCoefficient SEScalar0To1

Substance Concentration

Property Name Type Definition
Substance SESubstance SubstanceTable
Concentration SEScalarMassPerVolume

Gas Substance Quantity

The quantity of a gas substance in a gas compartment.

Property Name Type Definition
VolumeFraction SEScalar0To1 The amount of a substcane in the specified comparment as a fraction of all substance volume.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Volume SEScalarVolume The total volume of a substance in the specified compartment.

Substance Quantity

Basic Substance Quantity.

Liquid Substance Quantity

The quantity of a solid,liquid, or gas substance in a liquid compartment.

Property Name Type Definition
MassExcreted SEScalarMass The total mass of a substance excreted in the specified compartment.
MassCleared SEScalarMass The total mass of a substance cleared in the specified compartment.
MassDeposited SEScalarMass The total mass of a substance deposited on the wall of the compartment.
Mass SEScalarMass The total mass of a substance in the specified compartment.
Molarity SEScalarAmountPerVolume The molarity of a substance in the specified compartment.
PartialPressure SEScalarPressure The partial pressure of a substance in the specified compartment.
Saturation SEScalar0To1 The saturation of a substance in the specified compartment. (if applicable, like O2 and CO2)
Concentration SEScalarMassPerVolume The concentration of a substance in the specified compartment.

Gas Compartment

Property Name Type Definition
InFlow SEScalarVolumePerTime
OutFlow SEScalarVolumePerTime
Name String
SubstanceQuantities List of SEGasSubstanceQuantityGasSubstanceQuantityTable
Volume SEScalarVolume
Pressure SEScalarPressure

Thermal Compartment

Property Name Type Definition
HeatTransferRateIn SEScalarPower
Name String
Temperature SEScalarTemperature
HeatTransferRateOut SEScalarPower
Heat SEScalarEnergy

Tissue Compartment

Property Name Type Definition
TissueToPlasmaAlphaAcidGlycoproteinRatio SEScalar
Name String
AcidicPhospohlipidConcentration SEScalarMassPerMass
MatrixVolume SEScalarVolume
TissueToPlasmaLipoproteinRatio SEScalar
TotalMass SEScalarMass
TissueToPlasmaAlbuminRatio SEScalar
NeutralLipidsVolumeFraction SEScalar0To1
NeutralPhospholipidsVolumeFraction SEScalar0To1

Liquid Compartment

Property Name Type Definition
InFlow SEScalarVolumePerTime
OutFlow SEScalarVolumePerTime
Name String
SubstanceQuantities List of SELiquidSubstanceQuantityLiquidSubstanceQuantityTable
Volume SEScalarVolume
PH SEScalar
Pressure SEScalarPressure

Fluid Compartment

Property Name Type Definition
InFlow SEScalarVolumePerTime
OutFlow SEScalarVolumePerTime
Name String
Pressure SEScalarPressure
Volume SEScalarVolume

%

%

Scenario

Property Name Type Definition
Name String
EngineState String
Description String
InitialParameters SEScenarioInitialParameters ScenarioInitialParametersTable

Scenario Initial Parameters

Property Name Type Definition
PatientFile String
Patient SEPatient PatientTable